Tech, Health, and Innovation Funding and Support

Tech + Innovation Funding Alerts

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Updated Monthly. Original Publish Date: June 10, 2021

CrossComm is dedicated to helping innovators create meaningful value through technology. Part of that approach is to share resources that empower our common cause — making a positive impact. Our Tech + Innovation Funding Alerts is a collection of funds and resources, both nationally and locally, aimed at supporting the development of disruptive technologies towards social good. Below you’ll find a list of funding opportunities for innovators in health, science, and social change. For those of you who are local to the Research Triangle region, there is also a section of opportunities just for you. 

If you are a change agent who would like to support technological innovation, and have a resource or grant you would like to include in our alerts, contact


SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer-Relevant Technologies Toward Commercialization
Application Due: August 5, 2022
A major objective of the Federal SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of medical biotechnology products is often impeded by a significant funding gap, known as the "Valley of Death," between the end of the SBIR or STTR Phase II award and the commercialization stage. This Funding Opportunity Announcement (FOA) solicits SBIR grant applications from SBCs to support later-stage research and development (referred to as Phase IIB) for projects that were previously funded under SBIR or STTR Phase II awards from any Federal agency. The goal of this FOA and Phase IIB awards is to assist applicants in pursuing the next appropriate milestone(s) necessary to advance a promising product or service along a commercialization pathway. 

Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders
Application Due: August 15, 2022; February 14, 2023
This Funding Opportunity Announcement (FOA) encourages grant applications from small business concerns proposing research projects, directed towards commercialization, for the development of novel, evidence-based, FDA-regulated medical products addressing the needs of patients suffering from opioid use disorders (OUD) and/or stimulant use disorders (StUD). Applications received under this FOA may fall within two scientific areas, namely: (1) pharmacotherapeutics (small molecules and biologics) and (2) medical therapeutic and diagnostic devices, including software as a medical device. This FOA strives to contribute to the effort against the national opioid and psychostimulant emergency and offer new medical products for individuals, families, and communities affected by this devastating crisis. 

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD)
Application Due: September 5, 2022
As part of the National Institute on Aging's (NIA) strategic plan to support the development of innovative strategies and therapies to prevent, diagnose, and treat AD/ADRD, this FOA invites applications through NIA's Small Business Innovation Research Program (SBIR) to encourage research on and the commercialization of novel therapies, devices, products, and healthcare programs and practices to prevent the onset of AD/ADRD and to reduce their burden on individuals, their families, and society at large. Examples of research that might be supported by this FOA include, but are not limited to, the following: Augmentation of existing computerized cognitive interventions that can be individually tailored to engage, adapt, challenge, and optimize functional cognitive abilities to enhance cognitive functioning and performance of activities of daily living; and Development of interventions to remediate age-related cognitive decline, especially using technology platforms with wide acceptance among older adults; Biosensors and prosthetic devices, technologies, and related software development to aid in the assessment, diagnosis, and remediation of age-related cognitive decline; Machine-learning tools and cognitive batteries that can be integrated into Electronic Medical Records (EMR) for diagnosis of MCI and AD/ADRD.

HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management
Application Due: September 8, 2022
Purpose The purpose of this FOA aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management. Applications received under this FOA must fall within the scope of the HEAL Initiative, including but not limited to: Tools and technologies to better understand the biological underpinnings of chronic pain, including new screening tools and models focused on pain and development of pain therapies; Develop improved pain management strategies for acute and chronic pain conditions, including development of novel pain management technologies and devices, and objective pain measurement.

Technologies and Informatics Tools for Cancer Metabolomics
Application Due: September 22, 2022
This Notice of Special Interest (NOSI) is to alert the community that the National Cancer Institute (NCI) is seeking to support development of innovative technologies and informatics tools for metabolomics research by leveraging ongoing programs. The NCI seeks to stimulate technology development to facilitate transformational new approaches for cancer metabolomics and lipidomics research through the IMAT and ITCR programs. Therefore, this announcement seeks to address the need for new technologies designed explicitly to overcome technical challenges and advance cancer metabolomics.

Leveraging Health Information Technology (Health IT) to Address and Reduce Health Care Disparities
Application Due: October 5, 2022
This funding opportunity announcement (FOA) seeks to support research that examines the impact of leveraging health information technology (health IT) to reduce disparities in access to and utilization of health care services, patient-clinician communication, and health outcomes for populations that experience health disparities in the U.S.The 2020-2025 Federal Health IT Strategic Plan outlines a vision of health IT to improve population health, access, equity, safety, and reduce costs via health IT capabilities such as public health surveillance, telehealth, and remote monitoring (e.g., wearables; web enabled medical devices).

SBIR to Develop New Methods and Technologies for Assessment of Risk and for Early Diagnosis and Prognosis of Type 1 Diabetes
Application Due: October 7, 2022
Early identification of T1D risk and the onset of autoimmunity provides the basis for a variety of major ongoing studies seeking to prevent or delay the disease.Methods for more efficient identification of individuals at risk of T1D in particular children who may be eligible for preventative intervention would include low cost, high-throughput, fast, easy to use, accurate and predictive assays/devices that could be used at the point of care level and can become widely available. Application of such technologies could facilitate and expedite testing when effective ways to prevent or delay T1D become available and would be essential for identifying individuals who can benefit from such treatments.

Enabling SUD Digital Therapeutics Research to Improve Payor Adoption
Application Due: October 15, 2022
Purpose and Research Objectives Substance use disorders (SUDs) profoundly affect nearly every aspect of society. Drug and alcohol use in the United States costs $1.4 trillion in economic loss and societal harm annually. This includes $578 billion in economic loss and $874 billion in societal harm through quality-of-life adjustment and premature loss of life. Digital therapeutics (DTx) represent a new opportunity to address this significant public health challenge. In context of this FOA, the White House Office of National Drug Control Policy (ONDCP) has recently identified “reimbursement for digital treatment for addiction” as the priority in expanding access to evidence-based treatment. DTx is evidence-based therapeutic interventions enabled by high-quality software programs, aiming to prevent, manage, or treat a medical disorder or disease.

Mobile Health: Technology and Outcomes in Low and Middle Income Countries
Application Due: November 15, 2022
The purpose of this Funding Opportunity Announcement (FOA) is to encourage exploratory/developmental research applications that propose to study the development, validation, feasibility, and effectiveness of innovative mobile health (mHealth) interventions or tools specifically suited for low- and middle-income countries (LMICs) that utilize new or emerging technology, platforms, systems, or analytics. The overall goal of the program is to catalyze innovation through multidisciplinary research that addresses global health problems, develop an evidence base for the use of mHealth technology to improve clinical and public health outcomes, and strengthen mHealth research capacity in LMICs. Applicants are required to propose partnerships between at least one U.S. institution and one LMIC institution.


EPA Air Quality & Climate SBIR 
Application Due: August 23, 2022
The U.S. Environmental Protection Agency (EPA), as part of its Small Business Innovation Research (SBIR) program, is seeking proposals from the small businesses to develop novel environmental technologies in the following topics areas: Clean and Safe Water, Air Quality & Climate, Homeland Security, Circular Economy/Sustainable Materials, Safer Chemicals, Risk Assessment. Projects may include Software tools and machine-learning applications for systematic review in science assessment for chemical evaluation; Innovative technology solutions that build community resilience to disasters; Innovative technologies that help consumers prevent food waste in the acquisition, preparation, and storage of food.

Award For Outstanding Work In Digital Archaeology
Application Due: September 15, 2022
Digital technologies are driving important changes in archaeology. Despite the increasing acceptance of digital technology in daily life, however, determining how to assess digital scholarship has proved difficult: many universities remain unsure about how to evaluate digital work alongside more traditional forms of print publication when faced with tenure and promotion decisions. Recognizing the value of digital scholarship, and aiming to encourage its practice, the AIA offers this award to honor projects, groups, and individuals that deploy digital technology in innovative ways in the realms of excavation, research, teaching, publishing, or outreach.

NOAA Ocean Exploration Fiscal Year 2023 Funding Opportunity
Application Due: September 29, 2022
The NOAA Office of Ocean Exploration and Research, also known as NOAA Ocean Exploration, is soliciting proposals for projects to conduct or support ocean exploration of poorly understood regions of U.S. waters. NOAA Ocean Exploration is the only federal program dedicated to exploring the deep ocean, closing prominent gaps in our basic understanding of U.S. deep waters and the seafloor and delivering the ocean information needed to strengthen the economy, health, and security of our nation. Using the latest tools and technology, NOAA Ocean Exploration explores unknown or little known areas of our deep ocean, making discoveries of scientific, economic, and cultural value. Data collected are used to understand and maintain a healthy ocean, sustainably manage marine resources, accelerate the national economy, and build a better appreciation of the value and critical importance of the ocean in our everyday lives.

Advanced Technologies and Instrumentation (ATI) for Development of New Technologies and Instrumentation for Astronomy and Astrophysics
Application Due: November 15, 2022
The Advanced Technologies and Instrumentation (ATI) program provides individual investigator and collaborative research grants for development of new technologies and instrumentation for astronomy and astrophysics. The program supports overarching science objectives of the Division of Astronomical Sciences. Development of innovative, potentially transformative technologies are encouraged, even at high technical risk. Supported categories include but are not limited to: advanced technology development or concept feasibility studies and specialized instrumentation to enable new observations that are difficult or impossible to obtain with existing means. Proposals may include hardware and/or software development and/or analysis to enable new types of astronomical observations.

The MIT Sea Grant College Program 
Application Due: Various Deadlines and Ongoing
The MIT Sea Grant College Program is a Federal-Institute partnership that brings the research and engineering core of the Massachusetts Institute of Technology to bear on ocean-related challenges. Funded by the National Oceanic and Atmospheric Administration, the National Sea Grant College Program promotes the conservation and sustainable development of marine resources through research, education, and outreach.


Innovative Technology Experiences for Students and Teachers (ITEST)
Application Due: August 12, 2022
The economic prosperity and national security of the United States is reliant upon the nation’s capacity to remain globally competitive in the technological and computational fields. The nation’s competitiveness, however, is contingent upon its capacity to educate the next generation. Learning and teaching must be reimagined to better represent the diverse composition and perspective of our nation’s people and be expanded to encompass all pathways for students to receive a high-quality STEM education. A highly proficient and diverse technological and computational STEM workforce is needed to advance new discoveries in science, engineering, and technology in the service of the nation. ITEST is an applied research and development program with goals to advance the equitable and inclusive integration of technology in the learning and teaching of science, technology, engineering, or mathematics (STEM) from pre-kindergarten through high school. 

Interactive Digital Media STEM Resources for Pre-College and Informal Science Education Audiences (SBIR) 
Application Due: September 2, 2022
The educational objective of this FOA is to provide opportunities for eligible SBCs to submit NIH SBIR grant applications to develop IDM STEM products that address student career choice and health and medicine topics for: (1) pre-kindergarten to grade 12 (P-12) students and teachers or (2) informal science education (ISE) audiences. The second educational objective is to inform the American public that their quality of health is defined by lifestyle. If this message is understood, people can begin to live longer and reduce the healthcare burden to society. Therefore, this FOA also encourages IDM STEM products that will increase public health literacy and stimulate behavioral changes towards a healthier lifestyle. The research objective of this FOA is the development of new educational products that will advance our understanding of how IDM STEM-based gaming can improve student learning. It is anticipated that increasing underserved and minority student achievement in STEM fields through IDM STEM resources will encourage these students to pursue health-related careers that will increase their economic and social opportunities.

Research on Emerging Technologies for Teaching and Learning
Application Due: October 17, 2022
The purpose of the Research on Emerging Technologies for Teaching and Learning (RETTL)program is to fund exploratory and synergistic research in emerging technologies (to include, but not limited to, artificial intelligence (AI), robotics, and immersive or augmenting technologies) for teaching and learning in the future. The program accepts proposals that focus on learning, teaching, or a combination of both. The scope of the program is broad, with special interest in diverse learner/educator populations, contexts, and content, including teaching and learning in science, technology, engineering, and mathematics (STEM) and in foundational areas that enable STEM (e.g., self-regulation, literacy, communication, collaboration, creativity, and socio-emotional skills).

UNICEF Venture Fund
Application Due: Ongoing
The UNICEF Venture Fund makes $50–100K early stage investments in technologies for children developed by UNICEF country offices or companies in UNICEF programme countries. By providing flexible funding to early-stage innovators, it allows UNICEF to quickly assess, fund and grow open-source technology solutions that show potential to positively impact the lives of vulnerable children.


Application Due: August 29,2022 
NC Idea Seed offers early stage companies the critical funding they need to scale faster. Their $50K grants are awarded to innovative startups with a proven concept — even if they are not yet profitable. The funds, along with mentorship and guidance, push companies forward and reduce risk associated with growing startups.

NCBiotech’s Flash Grant program
Application Due: September 14, 2022
NCBiotech’s Flash Grant program aims to identify and energize the most creative ideas that exhibit early indications of commercial potential. Like a flash of inspiration, Flash Grants infuse funding at a critical early point when a small, targeted influx of funds can be crucial to shaping innovative research ideas into high potential life sciences technologies, particularly in emerging and converging life sciences sectors. This cycle is open to Clinician Innovators developing: Medical devices; Pharmaceuticals and biologics; Precision health solutions; Clinical software and workflow solutions. 

NC Biotechnology Center Innovation Impact Grant (IIG) FY2022
Application Due: October 12, 2022
The Innovation Impact Grant (IIG) program supports the purchase of research equipment for core facilities at academic or nonprofit institutions, fostering innovation within North Carolina’s life sciences ecosystem. Priority will be given to proposals that are most likely to have high impact at the applicant institution and in the broader life sciences research community.

First Flight Venture Center and BARDA DRIVE Health Security Accelerator
Various Projects
First Flight connects you with BARDA through the DRIVe (Division of Research, Innovation, and Ventures) initiative, a part of the Biomedical Advanced Research and Development Authority (BARDA) in the HHS Office of the Assistant Secretary for Preparedness and Response (ASPR). DRIVe’s mission is transforming Health Security by accelerating the research, development, and availability of transformative countermeasures to protect Americans from natural and intentional health security threats.