Tech + Innovation Funding Alerts

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Updated every first Friday of the month. First published date: June 10, 2021

CrossComm is dedicated to helping innovators create meaningful value through technology. Part of that approach is to share resources that empower our common cause — making a positive impact. Our Tech + Innovation Funding Alerts is a collection of funds and resources, both nationally and locally, aimed at supporting the development of disruptive technologies towards social good. Below you’ll find a list of funding opportunities for innovators in health, science, and social change. For those of you who are local to the Research Triangle region, there is also a section of opportunities just for you. 

If you are a change agent who would like to support technological innovation, and have a resource or grant you would like to include in our alerts, contact DeAnneCanieso@CrossComm.com.


Developing Digital Therapeutics for Substance Use Disorders 
Application Due: December 6, 2022 ; April 6, 2023; August 4, 2023
The purpose of this Funding Opportunity Announcement (FOA) is to accelerate the development of Digital Therapeutics (DTx) to treat Substance Use Disorders (SUDs). Advances in technology offer unprecedented opportunities to develop clinical-grade mobile, web, or other software-based platforms designed to deliver treatments that are safe and effective for SUD. FDA authorization of DTx can play an important role in increasing the availability of treatments to patients with SUD, although there are other pathways for dissemination of this class of intervention. The primary objective of this FOA is to move DTx to their next step in the development process, with the ultimate goal of generating new, FDA authorized, disseminated treatments for SUDs.

DoD Traumatic Brain Injury and Psychological Health, Clinical Trial Award
Application Due: December 8, 2022
The intent of the FY22 TBIPHRP CTA is to support the rapid implementation of clinical trials with the potential to have a significant impact on psychological health conditions and/or TBI through clinical applications, including healthcare products, technologies, and/or practice guidelines. Proposed research can be aligned with TBI, psychological health, or both. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, therapies, clinical guidance, behavioral interventions, emerging approaches and technologies, and/or new indications for products currently FDA-approved or - cleared.

DoD Traumatic Brain Injury and Psychological Health, Focused Program Award
Application Due: December 8, 2022
The intent of the FY22 TBIPHRP FPA is to optimize research and accelerate solutions to a critical question related to at least one sub-area within one of the three FY22 TBIPHRP FPA Focus Areas. The award mechanism supports development of a synergistic, multidisciplinary research program with the potential to have a significant impact on psychological health conditions and/or TBI through clinical applications, including healthcare products, technologies, and/or practice guidelines. Proposals/applications may propose applied/preclinical/clinical research and clinical trials. Clinical trials may be designed to evaluate promising new products, new indications, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies.

Developing a Public Health Tool to Predict the Virality of Vaccine Misinformation Narratives
Application Due: January 6, 2023
The purpose of this Notice of Funding Opportunity is to support research to develop a predictive forecasting model that identifies new or reemerging misinformation narratives that are likely to disseminate widely and have a high potential for impact on vaccine confidence. The information from this model will then be used to develop a tool that public health agencies could use to predict misinformation trends in the populations served. Finally, the researchers will evaluate the tool's predictive capabilities on both future social media misinformation narratives and real-world events.

Point-of-Care Technologies Research Network: Technology Research and Development Centers (TRDC)
Application Due: January 7, 2023
The purpose of this funding opportunity announcement is to solicit Technology Research and Development Center (TRDC) applications for the Point-of-Care Technologies Research Network (POCTRN). The POCTRN catalyzes innovation in medical technologies through a network model that enhances complementary strengths and builds multidisciplinary partnerships across scientific/technological, clinical, regulatory, and commercialization domains. Each TRDC will accelerate the development, validation, and deployment of point-of-care, home-based, and other innovative testing technologies in a specific area of health research. The POCTRN TRDCs will merge scientific and technological capabilities and expertise with clinical need and market demand to address unmet testing, monitoring, and treatment demands. This opportunity is open to all applicants, including the existing POCTRN grantees as well as new applicants.

Laboratories to Optimize Digital Health
Application Due: February 5, 2023; June 5, 2023; October 5, 2023
Digital health incorporates mobile health (mHealth) and health information technology (smartphones, wearable sensors, internet platforms, and electronic health records) with biological, social, and behavioral data. Digital health technology offers unprecedented opportunities to help consumers, clinicians, and researchers measure, manage, and improve health and productivity. These tools also have the potential to improve our understanding of mental illness, to track the course of illnesses and recovery, and to provide and enhance mental health care. NIMH seeks applications for innovative research projects to test strategies to increase the reach, efficiency, effectiveness, and quality of digital mental health interventions which may impact mental health outcomes, including suicide behaviors and serious mental illness. 

Leveraging Health Information Technology (Health IT) to Address and Reduce Health Care Disparities
Application Due: February 5, 2023
This funding opportunity announcement (FOA) seeks to support research that examines the impact of leveraging health information technology (health IT) to reduce disparities in access to and utilization of health care services, patient-clinician communication, and health outcomes for populations that experience health disparities in the U.S.The 2020-2025 Federal Health IT Strategic Plan outlines a vision of health IT to improve population health, access, equity, safety, and reduce costs via health IT capabilities such as public health surveillance, telehealth, and remote monitoring (e.g., wearables; web enabled medical devices).

Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders
Application Due: February 14, 2023
This Funding Opportunity Announcement (FOA) encourages grant applications from small business concerns proposing research projects, directed towards commercialization, for the development of novel, evidence-based, FDA-regulated medical products addressing the needs of patients suffering from opioid use disorders (OUD) and/or stimulant use disorders (StUD). Applications received under this FOA may fall within two scientific areas, namely: (1) pharmacotherapeutics (small molecules and biologics) and (2) medical therapeutic and diagnostic devices, including software as a medical device. This FOA strives to contribute to the effort against the national opioid and psychostimulant emergency and offer new medical products for individuals, families, and communities affected by this devastating crisis. 

Neuromodulation/Neurostimulation Device Development for Mental Health Applications
Application Due: February 16, 2023; June 16, 2023; October 16, 2023
The purpose of this funding opportunity announcement (FOA) is to encourage applications seeking to develop the next generation of brain stimulation devices for treating mental health disorders. Applications are sought that will either 1) develop novel brain stimulation devices or 2) significantly enhance, by means of hardware/software improvements, the effectiveness of brain stimulation devices that are currently U.S. Food and Drug Administration (FDA)-approved or cleared. Novel devices should move beyond existing electrical/magnetic stimulation and develop new stimulation techniques capable of increased spatiotemporal precision as well as multi-focal, closed-loop approaches. Applications seeking to develop new capabilities should focus on significant enhancement of the spatial resolution, depth of delivery, and/or precision of the device. Incremental changes to existing devices (e.g., software updates) are not within the scope of this announcement.

Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns 
Application Due: February 16, 2023; June 16, 2023; October 16, 2023
This FOA encourages research relevant to the development of novel screening approaches and/or therapeutic interventions for potentially fatal or disabling conditions that have been identified through newborn screening, as well as for "high priority" genetic conditions where screening may be possible in the near future. Having an accurate screening test, as well as demonstrating the benefits of early intervention or treatment, are important criteria for including a condition on a newborn screening panel. Expanded knowledge of the genetic and molecular basis for various conditions, as well as technological innovation, can potentially increase the ability to screen for many disorders. Unfortunately, the pace of developing effective treatments lags behind the pace of developing new screening technologies, which unfortunately limits the benefits of screening for some disorders.

Leading Edge Acceleration Projects (LEAP) in Health Information Technology
Application Due: Ongoing through September 30, 2027
While working to implement Cures Act provisions, ONC identified gaps with respect to leveraging EHR data to support population-level analyses and delivery of services, as well as integrating clinical knowledge into routine clinical practice. The reasons for these gaps range from a lack of data standards and interoperability to the digitization, integration, and presentation of new evidence into clinical workflows in safe, useful, and useable ways.Therefore, this funding opportunity will support innovative and breakthrough solutions critical to maximize the potential of health IT and achieve the goal of a transformed healthcare delivery system through various methods, such as:Determining the fundamental questions, the answers to which will identify barriers to nationwide interoperability and electronic exchange of health data.Engaging the health IT industry, along with academic researchers, to identify and develop innovative solutions that address barriers to interoperability.Disseminating findings from research while fostering collaboration, advancement, and implementation of solutions and lessons learned with the health IT industry.


Digital Humanities Advancement Grants, National Endowment for the Humanities
Application Due: January 12, 2023
The National Endowment for the Humanities (NEH) Office of Digital Humanities is accepting applications for the Digital Humanities Advancement Grants program. The program supports innovative, experimental, and/or computationally challenging digital projects leading to work that can scale to enhance scholarly research, teaching, and public programming in the humanities.

FY2023 Ocean Technology Transition Project
Application Due: January 17, 2023
The U.S. Integrated Ocean Observing System (IOOS®) is a national and regional partnership working to provide ocean, coastal and Great Lakes observations, data, tools, and forecasts to improve safety, enhance the economy, and protect our environment. To increase observational and technical capabilities we need smart investments to innovate sensors, data management, decision support products, and other technical capabilities that will improve our ability to monitor and forecast environmental conditions with greater efficiency. The primary objective of IOOS’ Ocean Technology Transition Project (OTT) is to reduce the Research to Operations transition period for ocean observing, product development, and data management technologies for the ocean, coastal and Great Lakes.

Build and Broaden (B2): Enhancing Social, Behavioral and Economic Science Research and Capacity at Minority-Serving Institutions
Application Due: January 19, 2023
Build and Broaden (B2) supports fundamental research and research capacity across disciplines at minority-serving institutions (MSIs) and encourages research collaborations with scholars at MSIs. Growing the science, technology, engineering and mathematics (STEM) workforce is a national priority. National forecasts of the impending shortage of workers with science and engineering skills and essential research workers underscore a need to expand opportunities to participate in STEM research.

Investigator Initiated Research in Computational Genomics and Data Science
Application Due: January 25, 2023
The purpose of this funding opportunity announcement (FOA) is to invite applications for a broad range of research efforts in computational genomics, data science, statistics, and bioinformatics relevant to one or both of basic or clinical genomic science, and broadly applicable to human health and disease. This FOA supports fundamental genomics research developing innovative analytical methodologies and approaches, early-stage development of tools and software, and refinement or hardening of software and tools of high value to the biomedical genomics community. Work supported under this FOA should be enabling for genomics and be generalizable or broadly applicable across diseases and biological systems. All applications should address how the methods would scale to address increasingly larger data sets.

Biomedical Technology Development and Dissemination Center
Application Due: January 26, 2023
This funding opportunity announcement (FOA) encourages grant applications for national Biomedical Technology Development and Dissemination (BTDD) Centers. The BTDD program supports the development of technologies once their feasibility has been established and the dissemination of these technologies to the wider biomedical research community. The program encourages investigators to propose projects that address any of the biomedical research areas within the mission of NIGMS. The Centers are required to make their technologies available to the research community in a sustainable manner, to provide user training, and to disseminate the Center’s technologies and results. Centers should be at the leading edge of their field with respect to both technology development and engagement of the relevant research community.

NLM Research Grants in Biomedical Informatics and Data Science
Application Due: February 5, 2023
The National Library of Medicine (NLM) supports innovative research and development in biomedical informatics and data science. This funding opportunity focuses on biomedical discovery and data-powered health, integrating streams of complex and interconnected research outputs that can be translated into scientific insights, clinical care, public health practices, and personal wellness. The scope of NLM's interest in these research domains is broad, with emphasis on new and innovative methods and approaches to foster data driven discovery in the biomedical and clinical health sciences as well as domain-independent, scalable, and reusable/reproducible approaches to discovery, curation, analysis, organization, and management of health-related digital objects

Institutes for Advanced Topics in the Digital Humanities
Application Due: February 15, 2023
This program aims to bring together humanities scholars, advanced graduate students, librarians, archivists, museum staff, computer scientists, information specialists, and others to learn about new tools, approaches, and technologies, and to foster relationships for future collaborations in the humanities. NEH encourages you to develop proposals for multidisciplinary teams that include the necessary range of intellectual, technical, and practical expertise. You may draw partners and collaborators from the private and public sectors and may include appropriate specialists from within and outside the United States.

BRAIN Initiative: Research Resource Grants for Technology Integration and Dissemination (U24 Clinical Trial Not Allowed)
Application Due: June 14, 2023
This funding opportunity announcement (FOA) supports efforts to disseminate resources for integration into neuroscience research practice. The resource(s) should be relevant to the goals of the BRAIN Initiative as outlined in the "BRAIN 2025: A Scientific Vision" and "The BRAIN Initiative 2.0: From Cells to Circuits, Toward Cures" and shared broadly to the neuroscience community. The resource(s) should address compelling needs of neuroscience researchers that are otherwise unavailable or impractical in their current form. Activities must include dissemination of an existing resource, and may include one or more of the following activities: distribution of tools and reagents; user training on the usage of new technologies or techniques; providing access to existing technology platforms and/or specialized facilities; minor improvements to increase the scale/efficiency of resource production and delivery; minor adaptations to meet the needs of a user community.

The MIT Sea Grant College Program 
Application Due: Various Deadlines and Ongoing
The MIT Sea Grant College Program is a Federal-Institute partnership that brings the research and engineering core of the Massachusetts Institute of Technology to bear on ocean-related challenges. Funded by the National Oceanic and Atmospheric Administration, the National Sea Grant College Program promotes the conservation and sustainable development of marine resources through research, education, and outreach.


Extreme Risk Protective Order and Firearm Crisis Intervention Training and Technical Assistance Initiative
Application Due: January 9, 2023
This solicitation seeks three training and technical assistance providers to support grantees selected through a companion solicitation, which provides funding to states and subrecipients for the creation and/or implementation of state crisis intervention court proceedings, extreme risk protection order programs, and related gun violence reduction programs/initiatives.

AgrAbility - Assistive Technology Program for Farmers with Disabilities
Application Due: January 19, 2023
NIFA requests applications for the Assistive Technology Program for Farmers with Disabilities through the AgrAbility program, for fiscal year (FY) 2022. The AgrAbility program works to increase the likelihood that farmers, farm workers and farm family members with disabilities, including veterans with disabilities, and their families who engage in farming, farm-related occupations, or are pursuing new farming opportunities, will experience success in agricultural production.

Building Resilient Infrastructure and Communities (BRIC)
Application Due: January 26, 2023
The Building Resilient Infrastructure and Communities (BRIC) program makes federal funds available to states, U.S territories, Indian tribal governments, and local communities for pre-disaster mitigation activities. With a general focus on disasters, risks, and hazards, including those associated with climate change, the guiding principles of the program include: encourage and enable innovation while allowing flexibility, consistency, and effectiveness; promote partnerships and enable high-impact investments to reduce risk from natural hazards with a focus on critical services and facilities, public infrastructure, public safety, public health, and communities.

Galvanizing Health Equity Through Novel and Diverse Educational Resources (GENDER) Research Education
Application Due: June 27, 2023
Specifically, this FOA aims to support courses that develop skills in multidimensional and intersectional health-related research and healthcare delivery. The format of the courses may involve a traditional in-person approach, online activities, a hybrid of both approaches, or other methods. The over-arching goal of this ORWH R25 program is to support educational activities that complement and/or enhance the training of a diverse workforce to meet the nation’s biomedical, behavioral and clinical research.   

UNICEF Venture Fund
Application Due: Ongoing
The UNICEF Venture Fund makes $50–100K early stage investments in technologies for children developed by UNICEF country offices or companies in UNICEF programme countries. By providing flexible funding to early-stage innovators, it allows UNICEF to quickly assess, fund and grow open-source technology solutions that show potential to positively impact the lives of vulnerable children.


NCBiotech’s Cycle 2 Flash Grant program
Deadline: December 7, 2022
NCBiotech’s Flash Grant program aims to identify and energize the most creative ideas that exhibit early indications of commercial potential. Like a flash of inspiration, Flash Grants infuse funding at a critical early point when a small, targeted influx of funds can be crucial to shaping innovative research ideas into high potential life sciences technologies, particularly in emerging and converging life sciences sectors. This cycle is open to Clinician Innovators developing: Medical devices; Pharmaceuticals and biologics; Precision health solutions; Clinical software and workflow solutions. 

NCBiotech: Company Funding, University Technology Development
Application Due: Varies
NCBiotech offers several funding programs designed to fill gaps in technology development and company growth. These funds help university researchers and companies conduct critical studies and reach significant development milestones that enable them to attract follow-on funding.

One North Carolina Small Business Program
Application Due: Varies
The One North Carolina Small Business Program helps fund North Carolina businesses in capital-intensive, high-risk industries in science, technology, engineering and math.  If your company wins a Phase I federal Small Business Innovation Research or Small Business Technology Transfer grant (SBIR/STTR), your money can go farther with matching dollars from our One NC Small Business Program.

First Flight Venture Center and BARDA DRIVE Health Security Accelerator
Various Projects
First Flight connects you with BARDA through the DRIVe (Division of Research, Innovation, and Ventures) initiative, a part of the Biomedical Advanced Research and Development Authority (BARDA) in the HHS Office of the Assistant Secretary for Preparedness and Response (ASPR). DRIVe’s mission is transforming Health Security by accelerating the research, development, and availability of transformative countermeasures to protect Americans from natural and intentional health security threats.